Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | P4HB | P07237 | 1/20 | 0.44 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.44 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865166 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL9332848 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL24804649 | 1.00 | LMNA (0.52) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL25736465 | 0.92 | LMNA (0.48) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL8002809 | 0.92 | CYP3A4 (0.46) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL827827 | 0.89 | NT5E (0.47) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL827826 | 0.89 | NT5E (0.47) | LMNAPOLBKMT2ATSHRCYP2D6 | |
| SCHEMBL17456128 | 0.89 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL17456127 | 0.89 | NT5E (0.48) | LMNAPOLBKMT2ACYP2D6ALDH1A1 | |
| SCHEMBL8699189 | 0.89 | TSHR (0.50) | LMNAPOLBKMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352811-A | To produce homoallylic alcohol, acylation, oxidation of double bond | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5158941-A | Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-27 | — | — | US | disclosed |