Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.39 |
| ▸ | ORAI2 | Q96SN7 | 4/20 | 0.39 |
| ▸ | ORAI3 | Q9BRQ5 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29706601 | 0.77 | ENPP2 (0.44) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL6678412 | 0.77 | ENPP2 (0.44) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL11645561 | 0.71 | CA1 (0.35) | ENPP2CA1CA2 | |
| SCHEMBL3196704 | 0.67 | ENPP2 (0.37) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL2885055 | 0.67 | LMNA (0.42) | ENPP2ORAI1ORAI2ORAI3TP53 | |
| SCHEMBL2260419 | 0.67 | CA1 (0.62) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL30689248 | 0.67 | CA1 (0.62) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| Potassium SCHEMBL8009526 | 0.65 | LMNA (0.41) | ENPP2ORAI1ORAI2ORAI3TP53 | |
| SCHEMBL31657742 | 0.65 | ENPP2 (0.39) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL5175329 | 0.64 | RXRA (0.42) | ENPP2ORAI1ORAI2ORAI3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011456-B1 | ORGANOTIN COMPOUNDS AND RESINS OR POLYMERS STABILIZED THEREWITH | M & T CHEMICALS, INC. (US) | 1983-09-07 | — | — | EP | disclosed |
| US-4254017-A | HEAT STABILIZER FOR POLYVINYL CHLORIDE | M&T CHEMICALS INC. (US) | 1981-03-03 | — | — | US | disclosed |
| EP-0011456-A1 | Organotin compounds and resins or polymers stabilized therewith | M & T CHEMICALS, INC. (US) | 1980-05-28 | — | — | EP | disclosed |