Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403639 | 0.87 | CA2 (0.43) | ENPP2HPGDTSHRMAPK1HSD17B10 | |
| SCHEMBL511746 | 0.79 | CA1 (0.39) | ENPP2ORAI1ORAI2ORAI3TSHR | |
| SCHEMBL3196690 | 0.75 | CA1 (0.31) | ENPP2CA1CA2 | |
| SCHEMBL6678412 | 0.71 | ENPP2 (0.44) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL29706601 | 0.71 | ENPP2 (0.44) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL7166372 | 0.67 | HPGD (0.51) | HPGDTSHRMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL11176830 | 0.67 | ENPP2 (0.41) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL29506645 | 0.67 | ALDH1A1 (0.40) | ENPP2ORAI1ORAI2ORAI3HPGD | |
| SCHEMBL2933439 | 0.67 | CA1 (0.54) | ENPP2ORAI1ORAI2ORAI3TSHR | |
| SCHEMBL3421122 | 0.67 | ALDH1A1 (0.40) | ENPP2ORAI1ORAI2ORAI3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671166-B2 | High internal free volume compositions for low-k dielectric and other applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-03-02 | — | — | US | disclosed |
| EP-1313785-B1 | COMPOSITION COMPRISING IPTYCENE POLYMERS WITH HIGH INTERNAL VOLUME | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-04-01 | — | — | EP | disclosed |
| US-7494698-B2 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080188634-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-08-07 | — | — | US | disclosed |
| WO-2007062210-A2 | HIGH INTERNAL FREE VOLUME COMPOSITIONS FOR LOW-K DIELECTRIC AND OTHER APPLICATIONS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070117954-A1 | High internal free volume compositions for low-k dielectric and other applications | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-24 | — | — | US | disclosed |
| US-20040170775-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-09-02 | — | — | US | disclosed |
| US-6783814-B2 | GRAFT POLYMER OF POROUS POLYMER AND INTERPENETRATING POLYMER NETWORK | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| EP-1313785-A2 | POLYMERS WITH HIGH INTERNAL FREE VOLUME | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002016463-A9 | POLYMERS WITH HIGH INTERNAL FREE VOLUME | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-04-03 | — | — | WO | disclosed |
| US-20020150697-A1 | Polymers with high internal free volume | NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA | 2002-10-17 | — | — | US | disclosed |
| WO-2002016463-A2 | POLYMERS WITH HIGH INTERNAL FREE VOLUME | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-02-28 | — | — | WO | disclosed |