SCHEMBL11178482

SCHEMBL11178482

O=C(Cc1ccccc1)Cc1cccc(F)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.55
CNR2 P34972 1/20 0.54
SIGMAR1 Q99720 2/20 0.49
SLC1A1 P43005 2/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
AKR1B1 P15121 1/20 0.48
CASP3 P42574 1/20 0.48
CASP7 P55210 1/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
POLB P06746 1/20 0.48
RAB9A P51151 1/20 0.48
NR4A2 P43354 2/20 0.47
HCAR2 Q8TDS4 1/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
VNN1 O95497 1/20 0.46
KCNQ2 O43526 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6864466 0.94 TAAR1 (0.50) SRCSLC1A1CES2CES1CASP3
SCHEMBL27814786 0.85 FFAR1 (0.49) SRCCNR2SIGMAR1SLC1A1MEN1
SCHEMBL8053109 0.85 VNN1 (0.49) SRCSLC1A1CES2CES1CASP3
SCHEMBL9113 0.84 AKR1B1 (0.58) SRCCNR2SLC1A1AKR1B1POLB
SCHEMBL20616356 0.84 AKR1B1 (0.64) SRCCNR2SIGMAR1SLC1A1CES2
SCHEMBL3371173 0.83 VNN1 (0.45) SRCSLC1A1CES2CES1CASP3
SCHEMBL8498964 0.83 VNN1 (0.48) SLC1A1CASP3CASP7MEN1KMT2A
SCHEMBL2999227 0.83 VNN1 (0.48) SRCSIGMAR1SLC1A1CASP3CASP7
Hydrochloric Acid SCHEMBL2531929 0.82 AKR1B1 (0.56) SRCCNR2SLC1A1AKR1B1NR4A2
SCHEMBL28191412 0.82 ALDH1A1 (0.62) CNR2CES2CES1AKR1B1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006359-B1 USE OF 1-ALKYL-3-PHENYLPYRIDINIUM SALTS AS HERBICIDES AND HERBICIDAL FORMULATIONS CONTAINING THE SALTS ELI LILLY AND COMPANY (US) 1983-09-28 EP disclosed
US-4218238-A Herbicidal 1-alkyl-3-phenylpyridinium salts ELI LILLY AND COMPANY (US) 1980-08-19 US disclosed
EP-0006359-A1 Use of 1-alkyl-3-phenylpyridinium salts as herbicides and herbicidal formulations containing the salts ELI LILLY AND COMPANY (US) 1980-01-09 EP disclosed
US-4174209-A Herbicidal 1-alkyl-3-phenylpyridinium salts ELI LILLY AND COMPANY (US) 1979-11-13 US disclosed