Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178482 | 0.94 | SRC (0.55) | VNN1SLC1A1CES2CES1RAB9A | |
| SCHEMBL8053109 | 0.90 | VNN1 (0.49) | TAAR1VNN1SLC1A1IDO1AGXT | |
| SCHEMBL3371173 | 0.88 | VNN1 (0.45) | TAAR1VNN1SLC1A1IDO1AGXT | |
| SCHEMBL8498964 | 0.88 | VNN1 (0.48) | TAAR1VNN1SLC1A1RAB9ACASP3 | |
| SCHEMBL2999227 | 0.88 | VNN1 (0.48) | TAAR1VNN1SLC1A1RAB9ACASP3 | |
| SCHEMBL27814786 | 0.87 | FFAR1 (0.49) | VNN1SLC1A1RAB9AMAPK8MEN1 | |
| Hydrochloric Acid SCHEMBL1150988 | 0.87 | TAAR1 (0.52) | TAAR1VNN1SLC1A1IDO1AGXT | |
| SCHEMBL11080103 | 0.85 | VNN1 (0.52) | TAAR1VNN1SLC1A1CASP3CASP7 | |
| SCHEMBL2209416 | 0.85 | VNN1 (0.49) | TAAR1VNN1RAB9AMAPK8MEN1 | |
| SCHEMBL22327488 | 0.85 | MAPK8 (0.51) | TAAR1VNN1SLC1A1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041182-A | A kind of 1,3- bis- replaces the preparation method of halogen phenylacetone | 玉林师范学院 | 2019-07-23 | — | — | CN | disclosed |
| CN-110002975-A | The preparation method and application of the substitution halogen phenylacetone of 1,3- bis- | 玉林师范学院 | 2019-07-12 | — | — | CN | disclosed |
| US-6797842-B2 | BY ASYMMETRICALLY REDUCING AN OPTICALLY ACTIVE IMINE, USING A HYDRIDE REDUCING AGENT TO CONVERT TO AN OPTICALLY ACTIVE SECONDARY AMINE, WHICH THEN UNDERGOES HYDROGENOLYSIS; HIGH OPTICAL PURITY, SIMPLE, EFFICIENT | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-09-28 | — | — | US | disclosed |
| US-20020103400-A1 | Process for producing optically active 1-(fluoro- or trifluoromethyl-substituted phenyl) ethylamine and process for purifying same | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-08-01 | — | — | US | disclosed |
| US-4102669-A | IN COTTON CULTURE | ELI LILLY AND COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4065290-A | Herbicidal β-phenyl-4-piperidinones | ELI LILLY AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103400-A1 | Process for producing optically active 1-(fluoro- or trifluoromethyl-substituted phenyl) ethylamine and process for purifying same | MAP2K5, MAP2K4, MAP2K1 | TAAR1 2742/4885VNN1 2486/4885SLC1A1 3617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.