SCHEMBL8498964

SCHEMBL8498964

CCC(=O)Cc1cccc(F)c1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
VNN1 O95497 1/20 0.48
RIPK1 Q13546 1/20 0.48
MAOB P27338 2/20 0.45
TAAR1 Q96RJ0 3/20 0.44
IDH1 O75874 1/20 0.44
SLC1A1 P43005 2/20 0.44
CASP3 P42574 1/20 0.43
CASP7 P55210 1/20 0.43
MAPK8 P45983 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6864466 0.88 TAAR1 (0.50) VNN1MAOBTAAR1SLC1A1CASP3
SCHEMBL11080103 0.86 VNN1 (0.52) VNN1RIPK1MAOBTAAR1SLC1A1
SCHEMBL11178482 0.83 SRC (0.55) VNN1SLC1A1CASP3CASP7MEN1
SCHEMBL8053109 0.83 VNN1 (0.49) VNN1MAOBTAAR1SLC1A1CASP3
SCHEMBL1538128 0.83 VNN1 (0.50) VNN1RIPK1MAOB
SCHEMBL2209416 0.82 VNN1 (0.49) VNN1MAOBTAAR1MAPK8MEN1
SCHEMBL23901663 0.82 IAPP (0.56) RIPK1MAOBTAAR1CASP3CASP7
SCHEMBL27590743 0.82 CES2 (0.50) RIPK1MEN1KMT2A
SCHEMBL2999227 0.81 VNN1 (0.48) VNN1TAAR1SLC1A1CASP3CASP7
SCHEMBL3371173 0.81 VNN1 (0.45) VNN1TAAR1SLC1A1CASP3CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136646-A Method for synthesizing benzyl alkyl ketone compound by visible light catalysis 中国科学院化学研究所 2025-06-13 CN disclosed
CN-116656257-B Explosion-proof anti-dazzle automobile film and preparation method thereof 精一门(常州)光学薄膜有限公司 2024-03-22 CN disclosed
CN-116656257-A Explosion-proof anti-dazzle automobile film and preparation method thereof 精一门(常州)光学薄膜有限公司 2023-08-29 CN disclosed
EP-0912494-A1 COUMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES NPS PHARMACEUTICALS, INC. (US) 1999-05-06 EP disclosed
WO-1998056752-A1 COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES NPS PHARMACEUTICALS, INC. (US) 1998-12-17 WO disclosed
EP-0831799-A1 COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS NPS PHARMACEUTICALS, INC. (US) 1998-04-01 EP disclosed
WO-1997046511-A1 COUMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES NPS PHARMACEUTICALS, INC. (US) 1997-12-11 WO disclosed
WO-1996040097-A1 COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS NPS PHARMACEUTICALS, INC. (US) 1996-12-19 WO disclosed
EP-0743853-A1 COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES NPS PHARMACEUTICALS, INC. (US) 1996-11-27 EP disclosed
WO-1995021612-A2 COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES NPS PHARMACEUTICALS, INC. (US) 1995-08-17 WO disclosed
US-4487969-A DIAZOTIZATION OF M-AMINOACETOPHENONE FOLLOWED BY HEAT DECOMPOSITION OLIN CORPORATION (US) 1984-12-11 US disclosed
EP-0105641-A1 Production of m-fluoroacetophenone OLIN CORPORATION (US) 1984-04-18 EP disclosed