Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | EDNRB | P24530 | 2/20 | 0.46 |
| ▸ | EDNRA | P25101 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087837 | 0.79 | MEN1 (0.52) | EDNRBEDNRAMAPTNPC1RAB9A | |
| SCHEMBL8087901 | 0.79 | MEN1 (0.52) | EDNRBEDNRAMAPTNPC1RAB9A | |
| SCHEMBL19164165 | 0.77 | MAPK1 (0.62) | EDNRBEDNRATDP1NPC1RAB9A | |
| 2-Methoxyanthraquinone SCHEMBL222927 | 0.76 | PTPN1 (0.60) | PTPN1MAPTTDP1NPC1HPGD | |
| SCHEMBL9765532 | 0.76 | S100A4 (0.50) | EDNRBEDNRAPTPN1MAPTRAB9A | |
| SCHEMBL4645032 | 0.74 | PTPN1 (0.58) | PTPN1MAPTTDP1NPC1HPGD | |
| SCHEMBL17439396 | 0.74 | MAPT (0.55) | PTPN1MAPTTDP1NPC1HPGD | |
| SCHEMBL6990493 | 0.72 | MAOB (0.52) | PTPN1MAPTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL23111380 | 0.71 | PTPRC (0.59) | PTPN1MAPTTDP1NPC1HPGD | |
| SCHEMBL2997273 | 0.71 | PTPN1 (0.54) | PTPN1MAPTTDP1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399141-A | 5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof | MERCK & CO., INC. (US) | 1983-08-16 | — | — | US | disclosed |