Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.50 |
| ▸ | EDNRB | P24530 | 5/20 | 0.45 |
| ▸ | EDNRA | P25101 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087901 | 0.83 | MEN1 (0.52) | S100A4EDNRBEDNRACYP1A2MAPK1 | |
| SCHEMBL8087837 | 0.83 | MEN1 (0.52) | S100A4EDNRBEDNRACYP1A2MAPK1 | |
| SCHEMBL19164165 | 0.81 | MAPK1 (0.62) | S100A4EDNRBEDNRACYP1A2MAPK1 | |
| SCHEMBL13789561 | 0.79 | S100A4 (0.41) | S100A4THRBMEN1CDC25BKMT2A | |
| SCHEMBL11178593 | 0.76 | MTNR1A (0.47) | EDNRBEDNRAMAPK1ALDH1A1MAPT | |
| SCHEMBL11493706 | 0.76 | S100A4 (0.46) | S100A4EDNRBEDNRACYP1A2MAPK1 | |
| SCHEMBL31318355 | 0.74 | GPR3 (0.46) | S100A4EDNRBEDNRACACNB4CACNA1A | |
| SCHEMBL19164428 | 0.74 | CYP1A2 (0.77) | S100A4EDNRBEDNRACYP1A2MAPK1 | |
| SCHEMBL155593 | 0.73 | S100A4 (0.87) | S100A4MAPK1ALDH1A1MAPTTHRB | |
| SCHEMBL29378883 | 0.73 | S100A4 (0.87) | S100A4MAPK1ALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272621-B1 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4845302-A | Preparation of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF AKTIENGSELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |