Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL672208 | 0.95 | TSHR (0.61) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL27949240 | 0.92 | TSHR (0.58) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL6795640 | 0.81 | LMNA (0.65) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL28884246 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL11010267 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL9672173 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL9720616 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL352057 | 0.81 | — | — | |
| Toluene SCHEMBL9006971 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 | |
| Toluene SCHEMBL27941911 | 0.81 | ACHE (0.85) | TSHRLMNAALOX12ACHETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4385050-A | Antihypertensive polypeptides | ARMOUR PHARMACEUTICAL COMPANY (US) | 1983-05-24 | — | — | US | disclosed |