SCHEMBL1118007

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1117996	0.86	GRM4 (0.37)	P2RX3P2RX2GRM5
	SCHEMBL1117942	0.85	HTT (0.44)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL4550899	0.83	TSHR (0.40)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL1118068	0.80	CSNK2A2 (0.38)	RAB9ASMN1; SMN2NPC1ALDH1A1L3MBTL1
	SCHEMBL1781189	0.78	RAB9A (0.38)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL1117979	0.78	PIK3CD (0.40)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL4550711	0.77	ALDH1A1 (0.37)	RAB9ASMN1; SMN2NPC1ALDH1A1RXFP1
	SCHEMBL1117951	0.73	TSHR (0.40)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL4550801	0.72	TSHR (0.39)	RAB9ASMN1; SMN2NPC1ALDH1A1KDM4E
	SCHEMBL1117877	0.72	POLB (0.42)	RAB9ASMN1; SMN2NPC1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.