Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 5/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4278130 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL19938159 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL2510562 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL16114092 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL13833323 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL24299397 | 0.86 | HINT1 (0.62) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL5354648 | 0.85 | HINT1 (0.67) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL14559274 | 0.85 | HINT1 (0.67) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL5354652 | 0.85 | HINT1 (0.67) | HINT1NT5EGSK3ARPS6KA3MAPK14 | |
| SCHEMBL16822314 | 0.85 | AHCY (0.60) | HINT1NT5ESTING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020196993-A1 | VARIANT PHOSPHORIBOSYL PYROPHOSPHATE AMIDOTRANSFERASE AND METHOD FOR PRODUCING PURINE NUCLEOTIDE BY USING SAME | 씨제이제일제당 (주) | 2020-10-01 | — | — | WO | disclosed |
| EP-2970360-A1 | RAS INHIBITORS AND USES THEREOF | Dana-Farber Cancer Institute, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014160200-A9 | RAS INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-11-27 | — | — | WO | disclosed |
| WO-2014160200-A1 | RAS INHIBITORS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |