Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11183504 | 0.85 | MAOA (0.41) | TNKS2 | |
| SCHEMBL11190992 | 0.84 | MAPT (0.39) | TNKS2GABBR2GABBR1TRPV3CYP11B1 | |
| SCHEMBL11185927 | 0.84 | LMNA (0.42) | TNKS2CYP1A2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL11181630 | 0.83 | MEN1 (0.40) | TNKS2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL11187875 | 0.83 | TNKS2 (0.39) | TNKS2HRH4RAB9A | |
| SCHEMBL11190196 | 0.83 | TNKS2 (0.39) | TNKS2HRH4ALDH1A1RAB9A | |
| SCHEMBL11192162 | 0.82 | TRPV3 (0.37) | GABBR2GABBR1TRPV3CYP11B1CYP11B2 | |
| SCHEMBL11184666 | 0.81 | CDK5 (0.39) | TNKS2RAB9A | |
| SCHEMBL11184224 | 0.81 | HRH2 (0.51) | TNKS2 | |
| SCHEMBL11179410 | 0.80 | DRD2 (0.36) | TRPV3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4402849-A | DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-09-06 | — | — | US | disclosed |
| EP-0031021-B1 | TETRAHYDROQUINAZOLINES, PROCESS FOR THEIR PREPARATION, LIQUID CRYSTALLINE DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK PATENT GmbH (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0031021-A1 | Tetrahydroquinazolines, process for their preparation, liquid crystalline dielectrics containing them and electro-optical display element | MERCK PATENT GmbH (DE) | 1981-07-01 | — | — | EP | disclosed |