Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11189117 | 1.00 | MEN1 (0.53) | MEN1LMNAKMT2ACTSLCTSS | |
| SCHEMBL11188002 | 0.91 | MEN1 (0.66) | MEN1LMNAKMT2ACTSLCTSS | |
| SCHEMBL11187997 | 0.91 | MEN1 (0.66) | MEN1LMNAKMT2ACTSLCTSS | |
| SCHEMBL11194945 | 0.85 | CTSK (0.62) | CTSLCTSSCTSBCTSK | |
| SCHEMBL11194939 | 0.85 | CTSK (0.62) | CTSLCTSSCTSBCTSK | |
| SCHEMBL11184923 | 0.83 | TACR1 (0.57) | CTSLCTSSCTSBCTSK | |
| SCHEMBL11184144 | 0.81 | GLS (0.52) | CTSLCTSSCTSBCA1CTSK | |
| SCHEMBL11184152 | 0.81 | GLS (0.52) | CTSLCTSSCTSBCA1CTSK | |
| SCHEMBL9403520 | 0.81 | POLB (0.59) | MEN1LMNAKMT2ACTSLCTSS | |
| SCHEMBL4075762 | 0.79 | CTSS (0.65) | MEN1LMNAKMT2ACTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382142-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS; LEUKEMIA | KOWA CO., LTD. (JP) | 1983-05-03 | — | — | US | disclosed |