Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.52 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GLS | O94925 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403461 | 0.90 | RAB9A (0.54) | RAB9AABCC8KCNJ11KDM4EGAA | |
| SCHEMBL9403509 | 0.85 | GLS (0.58) | ABCC8KCNJ11KDM4EGAAMEN1 | |
| SCHEMBL11189108 | 0.81 | MEN1 (0.53) | POLBKDM4EMEN1KMT2ALMNA | |
| SCHEMBL9403454 | 0.81 | MAPK1 (0.59) | ABCC8KCNJ11KDM4EGAAMEN1 | |
| SCHEMBL11189117 | 0.81 | MEN1 (0.53) | POLBKDM4EMEN1KMT2ALMNA | |
| SCHEMBL6968687 | 0.76 | MMP3 (0.56) | CTSLCTSS | |
| SCHEMBL6968692 | 0.76 | MMP3 (0.56) | CTSLCTSS | |
| SCHEMBL3612969 | 0.75 | SMN1; SMN2 (0.76) | RAB9AABCC8KCNJ11KDM4EGAA | |
| SCHEMBL4075762 | 0.75 | CTSS (0.65) | MEN1KMT2ALMNACTSLCTSS | |
| SCHEMBL14401772 | 0.74 | CTSD (0.71) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288735-A | Water soluble carbonic anhydrase inhibitor | TRAGER SEYMOUR F (US) | 1994-02-22 | — | — | US | disclosed |