Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185296 | 0.91 | ALDH1A1 (0.45) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11187012 | 0.89 | KDM4E (0.47) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11186809 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11186223 | 0.88 | ALDH1A1 (0.43) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11189697 | 0.87 | MAOB (0.47) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11193230 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11197178 | 0.85 | LMNA (0.41) | KDM4EALDH1A1APOBEC3GMAPTHPGD | |
| SCHEMBL11183238 | 0.85 | ADORA2B (0.42) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 | |
| SCHEMBL11187773 | 0.84 | MEN1 (0.36) | POLBMEN1KMT2AMAPTHTT | |
| SCHEMBL11194589 | 0.83 | FGFR1 (0.34) | KDM4EALDH1A1TSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4406897-A | 6-Aryl-4-hydrazinyl-s-triazin-2-ones | WILLIAM H. RORER, INC. (US) | 1983-09-27 | — | — | US | disclosed |