Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11188471 | 0.89 | ADORA2B (0.40) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11182815 | 0.88 | ADORA3 (0.40) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11191897 | 0.87 | MEN1 (0.46) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11197178 | 0.86 | LMNA (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL11189250 | 0.86 | ALDH1A1 (0.39) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11188735 | 0.86 | ADORA2B (0.38) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11185989 | 0.85 | ADORA2B (0.41) | ADORA2BADORA1ADORA2AADORA3NLRP3 | |
| SCHEMBL11189448 | 0.85 | KDM4E (0.47) | ALDH1A1KDM4EHPGDCYP2C9CYP1A2 | |
| SCHEMBL11190607 | 0.84 | KDM4C (0.43) | ADORA2BADORA1ADORA2AADORA3ALDH1A1 | |
| SCHEMBL11190678 | 0.84 | CRHR1 (0.35) | ALDH1A1KDM4EHPGDCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4406897-A | 6-Aryl-4-hydrazinyl-s-triazin-2-ones | WILLIAM H. RORER, INC. (US) | 1983-09-27 | — | — | US | disclosed |