Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11826206 | 0.83 | SRC (0.41) | BCHEDRD3HTR1AADRB3HTR2A | |
| SCHEMBL16812875 | 0.78 | PTGS1 (0.41) | BCHEDRD3HTR1AHTR2AHTR2C | |
| SCHEMBL6262678 | 0.76 | ALDH1A1 (0.46) | BCHEDRD3HTR1AADRB3HTR2A | |
| SCHEMBL2204495 | 0.75 | PTGS2 (0.56) | CXCL8DRD3HTR2CPTGS2MMP1 | |
| SCHEMBL11204698 | 0.74 | PTGS2 (0.47) | CXCL8BCHEDRD3HTR1AADRB3 | |
| SCHEMBL11195556 | 0.74 | NOX1 (0.44) | CXCL8BCHEDRD3HTR1AADRB3 | |
| SCHEMBL18797642 | 0.74 | PTGS2 (0.50) | CXCL8DRD3HTR2CPTGS2MMP1 | |
| SCHEMBL11818814 | 0.71 | PTGS2 (0.60) | CXCL8BCHEDRD3HTR1AADRB3 | |
| SCHEMBL27295189 | 0.71 | BCHE (0.46) | BCHEMMP8MAPTKDM4EALDH1A1 | |
| SCHEMBL12856670 | 0.70 | LMNA (0.44) | BCHEDRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068563-A2 | Heterocyclic acetic acid compounds and compositions for treating bone diseases | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |