Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488973 | 0.82 | HPGD (0.42) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| SCHEMBL9420910 | 0.78 | NPC1 (0.50) | PTGS2OPRK1PDE4DCXCL8PTGS1 | |
| SCHEMBL28242386 | 0.76 | ALDH1A1 (0.34) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| SCHEMBL27725631 | 0.75 | ALDH1A1 (0.41) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| Anisole SCHEMBL28140747 | 0.75 | CA4 (0.38) | ALDH1A1HPGDKDM4EDRD3BCHE | |
| SCHEMBL11821456 | 0.74 | PTGS2 (0.74) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| SCHEMBL7556216 | 0.74 | TRPA1 (0.49) | ALDH1A1HPGDKDM4EHTR2BMAPT | |
| SCHEMBL11190829 | 0.74 | CXCL8 (0.43) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| Acetic Acid SCHEMBL28941926 | 0.74 | HSD17B3 (0.42) | PTGS2OPRK1PDE4DALDH1A1HPGD | |
| SCHEMBL1470487 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EBCHEHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0068563-A2 | Heterocyclic acetic acid compounds and compositions for treating bone diseases | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |