Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25881 | 0.78 | ESR1 (0.58) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL14311097 | 0.69 | ESR1 (0.60) | ESR1ESR2LMNAHPGDHSD17B10 | |
| Pentachlorophenol SCHEMBL11741447 | 0.67 | MEN1 (0.56) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL1686572 | 0.66 | TSHR (0.53) | LMNAHPGDHSD17B10TSHRCYP3A4 | |
| SCHEMBL7157010 | 0.66 | ESR1 (0.52) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL526434 | 0.66 | ESR1 (0.52) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL6273601 | 0.64 | SENP1 (0.50) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL23790036 | 0.63 | KCNN4 (0.48) | ESR1ESR2LMNAHPGDHSD17B10 | |
| Pentachlorophenol SCHEMBL4335096 | 0.62 | CA12 (0.61) | ESR1ESR2LMNAHPGDHSD17B10 | |
| SCHEMBL678367 | 0.62 | ESR1 (0.62) | ESR1ESR2LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4394496-A | POLYEPOXEDES WITH GOOD HIGH TEMPERATURE PROPERTIES | THE DOW CHEMICAL COMPANY (US) | 1983-07-19 | — | — | US | disclosed |