Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TYR | P14679 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10767991 | 0.89 | ESR1 (0.60) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL526434 | 0.81 | ESR1 (0.52) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL9790808 | 0.77 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL678367 | 0.77 | ESR1 (0.62) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL4449332 | 0.77 | ESR1 (0.62) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL134173 | 0.77 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL9790796 | 0.77 | ESR1 (0.56) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL7929288 | 0.75 | KIF11 (0.58) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL237273 | 0.73 | LMNA (0.67) | ESR1ESR2CYP3A4LMNATYR | |
| SCHEMBL7949296 | 0.73 | TSHR (0.56) | TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216508-A1 | Polycarbonate and acrylonitrile-butadiene-styrene polymeric blends with improved impact resistance | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-11-20 | — | — | US | disclosed |
| US-4129594-A | Process for the manufacture of aromatic dicarboxylic acid chlorides | ALLIED CHEMICAL CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |