Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087486 | 0.94 | WDR5 (0.64) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL4839937 | 0.78 | WDR5 (0.90) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11187453 | 0.74 | ALDH1A1 (0.51) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL989261 | 0.72 | WDR5 (1.00) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11193638 | 0.72 | ALDH1A1 (0.41) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2716549 | 0.69 | LMNA (0.49) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11186755 | 0.69 | HSD17B10 (0.47) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11177118 | 0.69 | ALDH1A1 (0.61) | ALDH1A1NPC1LMNARAB9AHTT | |
| SCHEMBL19827152 | 0.68 | ROCK1 (0.69) | WDR5ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL11180957 | 0.68 | ALDH1A1 (0.39) | WDR5ALDH1A1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404205-A | CARDIOTONIC AGENTS; ANGINA PECTORIS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-09-13 | — | — | US | disclosed |