Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119516 | 0.98 | LMNA (0.33) | ALDH1A1NFE2L2TSHRMAOBCYP2A6 | |
| SCHEMBL5669653 | 0.93 | ALDH1A1 (0.35) | ALDH1A1NFE2L2TSHRMAOBCYP2A6 | |
| SCHEMBL5670111 | 0.83 | ALDH1A1 (0.38) | ALDH1A1NFE2L2TSHRMAOBCYP2A6 | |
| SCHEMBL5352063 | 0.78 | MAOB (0.41) | ALDH1A1NFE2L2TSHRMAOBLMNA | |
| SCHEMBL10522046 | 0.78 | MAOB (0.41) | ALDH1A1NFE2L2TSHRMAOBLMNA | |
| SCHEMBL9222592 | 0.77 | MAOB (0.39) | ALDH1A1NFE2L2TSHRMAOBLMNA | |
| SCHEMBL67469 | 0.72 | ALDH1A1 (0.41) | ALDH1A1NFE2L2TSHRMAOBCYP2A6 | |
| SCHEMBL10415151 | 0.71 | MAOB (0.42) | ALDH1A1NFE2L2TSHRMAOBLMNA | |
| SCHEMBL10415153 | 0.71 | MAOB (0.42) | ALDH1A1NFE2L2TSHRMAOBLMNA | |
| SCHEMBL18243166 | 0.69 | RXRA (0.38) | ALDH1A1TSHRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280706-A1 | LIPOPROTEIN LIPASE-ACTIVATING COMPOSITIONS COMPRISING BENZENE DERIVATES | Otsuka Pharmaceutical Factory, Inc. (JP) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009139076-A1 | LIPOPROTEIN LIPASE-ACTIVATING COMPOSITIONS COMPRISING BENZENE DERIVATES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2009-11-19 | — | — | WO | disclosed |