Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | HBB | P68871 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038657 | 1.00 | KDM4E (0.68) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL30603139 | 1.00 | KDM4E (0.68) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL14126140 | 0.95 | KDM4E (0.62) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL31500228 | 0.95 | KDM4E (0.61) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL20535915 | 0.94 | KDM4E (0.62) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL11194565 | 0.92 | KDM4E (0.61) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL9594726 | 0.92 | KDM4E (0.57) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL12285138 | 0.88 | KDM4E (0.55) | KDM4EKMT2AMEN1APPHSD17B10 | |
| SCHEMBL31500219 | 0.87 | KDM4E (0.53) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A | |
| SCHEMBL6778691 | 0.86 | APP (0.69) | KDM4EPHLPP2ADORA2ACYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116715602-A | Fluorenyl oxalyl diamine compound, derivative and application thereof | 华东理工大学 | 2023-09-08 | — | — | CN | claimed |
| EP-3049083-A2 | COMPOUNDS FOR INHIBITION OF UNREGULATED CELL GROWTH | Godavari Biorefineries Ltd. (IN) | 2016-08-03 | — | — | EP | claimed |
| US-20160214941-A1 | Compounds for lnhibition of Unregulated Cell Growth | GODAVARI BIOREFINERIES LIMITED (IN) | 2016-07-28 | — | — | US | claimed |
| WO-2015044960-A2 | COMPOUNDS FOR INHIBITION OF UNREGULATED CELL GROWTH | GODAVARI BIOREFINERIES LIMITED (IN) | 2015-04-02 | — | — | WO | claimed |
| WO-2004061416-A2 | METHODS FOR ATTACHING MOLECULES | GENORX, INC. (US) | 2004-07-22 | — | — | WO | claimed |
| US-20040048241-A1 | Methods for attaching molecules | GENORX, INC. | 2004-03-11 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| US-5886185-A | ANTITUMOR AGENTS, ANTICARCINOGENIC AGENTS | DEVELOPMENT CENTER FOR BIOTECHNOLOY (TW) | 1999-03-23 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-12247246-B2 | Identification of inhibitors of TcpC and TIR NADase activity | WASHINGTON UNIVERSITY (US) | 2025-03-11 | — | — | US | disclosed |
| US-20230301984-A1 | CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION | THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303618-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | REYOUNG CORPORATION (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303618-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | REYOUNG CORPORATION (US) | 2023-09-28 | — | — | US | disclosed |
| CN-116715602-A | Fluorenyl oxalyl diamine compound, derivative and application thereof | 华东理工大学 | 2023-09-08 | — | — | CN | disclosed |
| EP-0436582-A1 | PHOSPHOROTHIOATE AND NORMAL OLIGODEOXYNUCLEOTIDES WITH 5'-LINKED ACRIDINE | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1991-07-17 | — | — | EP | disclosed |
| EP-0406309-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | THE UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1990003383-A1 | PHOSPHOROTHIOATE AND NORMAL OLIGODEOXYNUCLEOTIDES WITH 5'-LINKED ACRIDINE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1990-04-05 | — | — | WO | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |
| US-3948920-A | New anti-malarial agents | AKTIEBOLAGET ASTRA (SW) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247246-B2 | Identification of inhibitors of TcpC and TIR NADase activity | NADK, NAPRT, TIPARP | KDM4E 3114/4885PHLPP2 3053/4885ADORA2A 4308/4885 |
| US-20230301984-A1 | CYCLIC COMPOUNDS FOR USE IN TREATING RETINAL DEGENERATION | ALDH1A2, PDE6D, PDE6C | KDM4E 3316/4885PHLPP2 1530/4885ADORA2A 2888/4885 |
| US-20160214941-A1 | Compounds for lnhibition of Unregulated Cell Growth | MKI67, LYAR, CCNI | KDM4E 2994/4885PHLPP2 2546/4885ADORA2A 3702/4885 |
| US-20230303618-A1 | TRIPTOLIDE CONJUGATES AND USES THEREOF | TLR9, XIAP, ENPP2 | KDM4E 2714/4885PHLPP2 816/4885ADORA2A 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.