Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8798050 | 0.85 | PPARG (0.54) | CYSLTR2CYSLTR1PPARGLMNAMAPT | |
| SCHEMBL5393586 | 0.84 | ALDH1A1 (0.50) | MAPTKMT2AL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL9214705 | 0.81 | LMNA (0.61) | CYSLTR2CYSLTR1PPARGLMNAMAPT | |
| SCHEMBL11605622 | 0.81 | PPARG (0.60) | CYSLTR2CYSLTR1PPARGLMNAMAPT | |
| SCHEMBL7639583 | 0.81 | L3MBTL1 (0.67) | CYSLTR2CYSLTR1LMNAMAPTMEN1 | |
| SCHEMBL28515930 | 0.81 | L3MBTL1 (0.67) | CYSLTR2CYSLTR1LMNAMAPTMEN1 | |
| SCHEMBL3081241 | 0.81 | L3MBTL1 (0.67) | CYSLTR2CYSLTR1LMNAMAPTMEN1 | |
| SCHEMBL7636542 | 0.81 | L3MBTL1 (0.67) | CYSLTR2CYSLTR1LMNAMAPTMEN1 | |
| SCHEMBL28356201 | 0.80 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PPARGLMNAMAPT | |
| SCHEMBL29033404 | 0.79 | PPARG (0.58) | CYSLTR2CYSLTR1PPARGLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421924-A | FROM GULONO-1,4-LACTONE | PFIZER INC. (US) | 1983-12-20 | — | — | US | disclosed |
| US-4283340-A | VITAMINS | PFIZER INC. (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0000243-B1 | PROCESS FOR PREPARING 3,5:4,6- PROTECTED DERIVATIVES OF L- OR D- GULONIC ACID, THEIR USE IN PREPARING 2- KETO-L- OR D- GULONIC ACID OR THEIR ESTERS OR L- OR D- ASCORBIC ACID, AND CERTAIN NOVEL 2-NITRATO-GULONATE INTERMEDIATES | PFIZER INC. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4232168-A | OXIDATION, HYDROLYSIS | PFIZER INC. (US) | 1980-11-04 | — | — | US | disclosed |
| EP-0000243-A1 | Process for preparing 3,5:4,6- protected derivatives of L- or D- gulonic acid, their use in preparing 2- keto-L- or D- gulonic acid or their esters or L- or D- ascorbic acid, and certain novel 2-nitrato-gulonate intermediates | PFIZER INC. (US) | 1979-01-10 | — | — | EP | disclosed |