Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 9/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.48 |
| ▸ | DRD3 | P35462 | 8/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412262 | 0.89 | DRD4 (0.60) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL11194558 | 0.88 | DRD4 (0.59) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL9412123 | 0.87 | DRD4 (0.58) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL9412142 | 0.85 | DRD4 (0.61) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL23765267 | 0.83 | DRD4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL11197642 | 0.81 | ALDH1A1 (0.69) | SLC6A4SLC6A2HTR1ADRD4KCNH2 | |
| SCHEMBL10679019 | 0.77 | DRD2 (0.59) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL11200462 | 0.77 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL11196775 | 0.77 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1ADRD4 | |
| SCHEMBL23097597 | 0.76 | DRD2 (0.66) | SLC6A4HTR1ADRD4KCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |