Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | DRD3 | P35462 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194558 | 0.85 | DRD4 (0.59) | DRD4DRD2DRD3LMNATSHR | |
| Hydrochloric Acid SCHEMBL9412123 | 0.84 | DRD4 (0.58) | DRD4DRD2DRD3LMNATSHR | |
| SCHEMBL9412262 | 0.84 | DRD4 (0.60) | DRD4DRD2DRD3ALDH1A1SLC6A4 | |
| SCHEMBL11196367 | 0.83 | SLC6A4 (0.52) | DRD4DRD2DRD3ALDH1A1LMNA | |
| SCHEMBL11197642 | 0.83 | ALDH1A1 (0.69) | DRD4DRD2DRD3ALDH1A1LMNA | |
| SCHEMBL9412142 | 0.82 | DRD4 (0.61) | DRD4DRD2DRD3ALDH1A1SLC6A4 | |
| SCHEMBL9128429 | 0.76 | SLC6A4 (0.68) | ALDH1A1LMNASLC6A4HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL11193573 | 0.76 | DRD2 (0.55) | DRD4DRD2DRD3SLC6A4HTR1A | |
| Hydrochloric Acid SCHEMBL11193566 | 0.76 | DRD2 (0.55) | DRD4DRD2DRD3SLC6A4HTR1A | |
| SCHEMBL3128791 | 0.74 | CRBN (0.57) | DRD4DRD2DRD3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021160131-A1 | FIBROTIC DISEASE MECHANISM AND THERAPEUTIC DRUG THEREFOR | 广州市妇女儿童医疗中心 | 2021-08-19 | — | — | WO | disclosed |