Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP4 | P49662 | 1/20 | 0.54 |
| ▸ | CASP5 | P51878 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825748 | 0.81 | MEN1 (0.60) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12511057 | 0.79 | ACHE (0.74) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11202780 | 0.79 | POLB (0.56) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL11196310 | 0.79 | KMT2A (0.52) | MEN1KMT2AALDH1A1KDM4EACHE | |
| SCHEMBL10856538 | 0.76 | GAA (0.58) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL2372693 | 0.74 | ACHE (0.70) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9621558 | 0.73 | ACHE (0.65) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL4586698 | 0.73 | ACHE (0.69) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL14351628 | 0.72 | ACHE (0.68) | POLBMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL8309423 | 0.72 | MEN1 (0.63) | POLBMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |