Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | TRPC5 | Q9UL62 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202780 | 0.84 | POLB (0.56) | KMT2AKDM4ELMNATNKSPARP1 | |
| SCHEMBL10856538 | 0.81 | GAA (0.58) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL11196682 | 0.79 | POLB (0.60) | KMT2AKDM4ELMNAMEN1ACHE | |
| SCHEMBL16825859 | 0.79 | KMT2A (0.52) | KMT2AKDM4ELMNATNKSPARP1 | |
| SCHEMBL11196110 | 0.78 | ALDH1A1 (0.50) | KMT2ALMNAMEN1ACHEALDH1A1 | |
| SCHEMBL11206897 | 0.77 | ALDH1A1 (0.54) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL11194501 | 0.75 | LMNA (0.51) | KMT2AKDM4ELMNATNKSPARP1 | |
| SCHEMBL10851723 | 0.74 | TNKS (0.50) | KMT2AKDM4ETNKSPARP1TNKS2 | |
| SCHEMBL11200198 | 0.74 | ALDH1A1 (0.45) | KMT2AKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL11205350 | 0.73 | HTR1A (0.53) | KDM4ELMNAALDH1A1HTR7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |