Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP4 | P49662 | 1/20 | 0.45 |
| ▸ | CASP5 | P51878 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200914 | 0.92 | PARP1 (0.36) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL5174107 | 0.73 | CYP1A2 (0.37) | CASP1ACHESMN1; SMN2PKM | |
| SCHEMBL5376134 | 0.71 | CHRM5 (0.84) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL11596303 | 0.71 | CHRM5 (0.84) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL12005398 | 0.68 | MAPT (0.56) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL11194501 | 0.68 | LMNA (0.51) | DRD4 | |
| SCHEMBL23173406 | 0.66 | CASP1 (0.60) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL22903468 | 0.65 | CHIA (0.39) | — | |
| SCHEMBL20643257 | 0.65 | CHRM5 (1.00) | CASP1CASP4CASP5CHRM5ADRA2C | |
| SCHEMBL3439903 | 0.65 | CHRM5 (0.90) | CASP1CASP4CASP5CHRM5ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |