Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.40 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196110 | 0.89 | ALDH1A1 (0.50) | LMNAALDH1A1GAATSHRHTT | |
| SCHEMBL11197047 | 0.89 | KDM4E (0.52) | GAAKDM4EMAPK1DRD4 | |
| SCHEMBL10856538 | 0.88 | GAA (0.58) | LMNAALDH1A1GAATSHRHTT | |
| SCHEMBL10851723 | 0.87 | TNKS (0.50) | ALDH1A1GAATSHRHTTTNKS | |
| SCHEMBL10860653 | 0.85 | SIGMAR1 (0.54) | LMNAGAATSHRHTTMEN1 | |
| SCHEMBL11201299 | 0.85 | USP2 (0.50) | ALDH1A1GAATSHRUSP2HSD17B10 | |
| SCHEMBL11197942 | 0.84 | HRH3 (0.45) | LMNAGAATSHRHTTMEN1 | |
| SCHEMBL11200656 | 0.81 | SIGMAR1 (0.57) | LMNAALDH1A1GAATSHRHTT | |
| SCHEMBL11206897 | 0.79 | ALDH1A1 (0.54) | LMNAALDH1A1TSHRHTTKDM4E | |
| SCHEMBL10690328 | 0.77 | LMNA (0.80) | LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |