Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045867 | 0.90 | ALDH1A1 (0.62) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL9541390 | 0.89 | KDM4E (0.58) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL3142619 | 0.84 | TYK2 (0.55) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL22717132 | 0.84 | RAB9A (0.52) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL220681 | 0.84 | NPC1 (0.64) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL1363543 | 0.84 | TYK2 (0.55) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL4954916 | 0.84 | NPC1 (0.56) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL24001 | 0.84 | MAPT (0.66) | NPC1RAB9AHPGDALDH1A1HTT | |
| SCHEMBL1536363 | 0.84 | HTT (0.58) | NPC1RAB9AHPGDALDH1A1CYP3A4 | |
| SCHEMBL3124091 | 0.84 | NPC1 (0.72) | NPC1RAB9AHPGDALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897075-B | Green synthesis method of sucralose-6-acetate | 盐城捷康三氯蔗糖制造有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-4414220-A | HUPOGLYCEMIC, ANTIDIABETIC | PFIZER INC. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4333932-A | DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC | PFIZER INC. (US) | 1982-06-08 | — | — | US | disclosed |
| US-4220650-A | HYPOGLYCEMIC | PFIZER INC. (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0010896-A1 | Organic diamine compounds for use as oral hypoglycemic agents and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-05-14 | — | — | EP | disclosed |