Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197823 | 0.90 | NPC1 (0.55) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL13094612 | 0.88 | ALDH1A1 (0.71) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL3037245 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HPGDCYP3A4MAPK1RAB9A | |
| SCHEMBL11699427 | 0.83 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL2305372 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL9541390 | 0.80 | KDM4E (0.58) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL696853 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL473972 | 0.79 | ALDH1A1 (0.65) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL22717132 | 0.79 | RAB9A (0.52) | ALDH1A1HPGDCYP3A4MAPK1MAPT | |
| SCHEMBL220681 | 0.79 | NPC1 (0.64) | ALDH1A1HPGDCYP3A4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7727558-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| EP-1237872-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2008-02-27 | — | — | EP | disclosed |
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. | 2007-06-21 | — | — | US | disclosed |
| US-7208483-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-7186414-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1676832-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-6991798-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-12-18 | — | — | US | disclosed |
| US-20030216589-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2003-11-20 | — | — | US | disclosed |
| US-6627228-B1 | Polymeric delivery agents and delivery agents compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-09-30 | — | — | US | disclosed |
| EP-1237872-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1146860-A4 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECH INC (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1146860-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | Emisphere Technologies, Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2001044199-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2001-06-21 | — | — | WO | disclosed |
| EP-1102742-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000040203-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-07-13 | — | — | WO | disclosed |
| WO-2000007979-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | ALDH1A1 2208/4885HPGD 861/4885CYP3A4 3303/4885 |
| US-20030216589-A1 | Compounds and compositions for delivering active agents | IDUA, ALG1, APOB | ALDH1A1 3939/4885HPGD 2736/4885CYP3A4 4837/4885 |
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | LPXN, PGF, TTPA | ALDH1A1 3038/4885HPGD 583/4885CYP3A4 2850/4885 |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | ALDH1A1 2208/4885HPGD 861/4885CYP3A4 3303/4885 |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | LPXN, PGF, TTPA | ALDH1A1 3038/4885HPGD 583/4885CYP3A4 2850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.