Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814370 | 0.84 | PTGS2 (0.46) | THRATHRBMTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL8573202 | 0.82 | THRA (0.46) | THRATHRBELANEALOX15MTNR1A | |
| SCHEMBL1019194 | 0.81 | ELANE (0.47) | THRATHRBELANEALOX15L3MBTL1 | |
| SCHEMBL1789816 | 0.81 | THRA (0.58) | THRATHRBELANEKDM4EMEN1 | |
| SCHEMBL11200666 | 0.81 | THRA (0.48) | THRATHRBELANEALOX15MTNR1A | |
| SCHEMBL30399402 | 0.81 | THRA (0.58) | THRATHRBELANEKDM4EMEN1 | |
| SCHEMBL10670224 | 0.78 | EPHX1 (0.48) | THRATHRBELANEALOX15L3MBTL1 | |
| SCHEMBL11147730 | 0.78 | THRA (0.68) | THRATHRBKDM4EMEN1RECQL | |
| SCHEMBL21647799 | 0.78 | ALDH1A1 (0.43) | ELANEALOX15MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL11197839 | 0.78 | THRA (0.43) | THRATHRBELANEALOX15MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |