Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7301805 | 0.84 | ALOX15 (0.43) | ALDH1A1SMN1; SMN2HPGDHTTALOX15 | |
| SCHEMBL8084797 | 0.83 | NPC1 (0.47) | ALDH1A1SMN1; SMN2HPGDHTTALOX15 | |
| SCHEMBL8072579 | 0.82 | CYP1A2 (0.51) | SMN1; SMN2ALOX15LMNAKDM4ETDP1 | |
| SCHEMBL11685011 | 0.82 | KDM4E (0.44) | ALDH1A1SMN1; SMN2ALOX15LMNAKDM4E | |
| SCHEMBL8435546 | 0.81 | ALOX15 (0.55) | ALDH1A1SMN1; SMN2HPGDALOX15KDM4E | |
| SCHEMBL8081153 | 0.81 | LMNA (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4EMAPT | |
| SCHEMBL26698283 | 0.81 | LMNA (0.46) | ALDH1A1SMN1; SMN2HPGDHTTALOX15 | |
| SCHEMBL6249085 | 0.80 | L3MBTL1 (0.59) | ALDH1A1ALOX15KDM4ETDP1ELANE | |
| SCHEMBL5311090 | 0.80 | L3MBTL1 (0.59) | ALDH1A1SMN1; SMN2HPGDHTTALOX15 | |
| SCHEMBL8081134 | 0.79 | LMNA (0.59) | ALDH1A1LMNAKDM4EMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020027150-A1 | BENZENE DERIVATIVE | 小野薬品工業株式会社 | 2020-02-06 | — | — | WO | disclosed |