Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196859 | 0.90 | LMNA (0.49) | CASRALDH1A1HTTPOLBLMNA | |
| SCHEMBL11200148 | 0.88 | NPC1 (0.52) | KMT2AMEN1ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL11195367 | 0.84 | CASR (0.57) | CASRKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11193136 | 0.82 | KMT2A (0.48) | KMT2AMEN1ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL11197946 | 0.82 | NPC1 (0.48) | KMT2AMEN1ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL11198135 | 0.79 | NPC1 (0.44) | KMT2AMEN1ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL11200538 | 0.78 | SMN1; SMN2 (0.57) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL11198673 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1MAPTPOLB | |
| SCHEMBL11198968 | 0.78 | CASR (0.56) | CASRKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL11200409 | 0.78 | SMN1; SMN2 (0.49) | KMT2AMEN1ALDH1A1NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379926-A | DIURETICS | AYERST, MCKENNA & HARRISON LTD. (CA) | 1983-04-12 | — | — | US | disclosed |