SCHEMBL1119973

SCHEMBL1119973

COCCc1cnc(C(F)(F)F)s1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CACNA1H O95180 1/20 0.32
EGLN2 Q96KS0 1/20 0.31
EGLN1 Q9GZT9 1/20 0.31
EGLN3 Q9H6Z9 1/20 0.31
SCD O00767 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21939963 0.82 MEN1 (0.37) ALDH1A1HPGDHTTSMN1; SMN2EGLN2
SCHEMBL27780056 0.77 EGLN2 (0.30) EGLN2EGLN1EGLN3
SCHEMBL8241659 0.76 FDPS (0.37) ALDH1A1CACNA1HEGLN2EGLN1EGLN3
SCHEMBL32667225 0.74 MEN1 (0.32)
SCHEMBL8751632 0.74 SLC6A3 (0.37) ALDH1A1SMN1; SMN2
SCHEMBL17263320 0.73 SLC6A3 (0.34) CACNA1HEGLN2EGLN1EGLN3
SCHEMBL18641548 0.72 CACNA1G (0.31) CACNA1HEGLN2EGLN1EGLN3
SCHEMBL13563819 0.72 EGLN2 (0.31) ALDH1A1EGLN2EGLN1EGLN3
SCHEMBL7769591 0.72 ALDH1A1 (0.34) ALDH1A1EGLN2EGLN1EGLN3
SCHEMBL1959957 0.72 EGLN2 (0.31) ALDH1A1EGLN2EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2381781-A1 METHOD FOR IMPROVED USE OF THE PRODUCTION POTENTIAL OF GENETICALLY MODIFIED PLANTS Bayer CropScience AG (DE) 2011-11-02 EP disclosed
EP-2323488-A2 METHOD FOR IMPROVING PLANT GROWTH Bayer CropScience AG (DE) 2011-05-25 EP disclosed
EP-2280608-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS Bayer CropScience Aktiengesellschaft (DE) 2011-02-09 EP disclosed
WO-2010075966-A1 METHOD FOR IMPROVED USE OF THE PRODUCTION POTENTIAL OF GENETICALLY MODIFIED PLANTS BAYER CROPSCIENCE AG (DE) 2010-07-08 WO disclosed
WO-2010022897-A2 METHOD FOR IMPROVING PLANT GROWTH BAYER CROPSCIENCE AG (DE) 2010-03-04 WO disclosed
WO-2009135613-A1 SYNERGISTIC ACTIVE INGREDIENT COMBINATIONS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2009-11-12 WO disclosed