Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10759635 | 0.92 | KDM4E (0.39) | THRBTHRAPOLBMEN1KMT2A | |
| SCHEMBL11202177 | 0.82 | POLB (0.37) | THRBTHRAPOLBMEN1KMT2A | |
| SCHEMBL28725210 | 0.78 | ESR2 (0.40) | POLBMEN1KMT2APSMB5SMN1; SMN2 | |
| SCHEMBL11201347 | 0.77 | PDCD1 (0.40) | THRBPOLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL930457 | 0.73 | IDO1 (0.41) | TDP1ESR2ALDH1A1HTT | |
| SCHEMBL28529269 | 0.72 | PTPN1 (0.52) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8752792 | 0.70 | MEN1 (0.51) | POLBMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL128036 | 0.70 | ESR2 (0.47) | POLBMEN1KMT2APSMB5ESR2 | |
| SCHEMBL11197019 | 0.70 | HTR7 (0.49) | KMT2ATDP1C3AR1TSHRMAPK1 | |
| SCHEMBL16245270 | 0.70 | PDCD1 (0.47) | POLBMEN1KMT2ATP53ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |