Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991545 | 0.91 | HTR7 (0.45) | PDCD1CD274LMNAALDH1A1HTT | |
| SCHEMBL11206708 | 0.82 | CD274 (0.44) | PDCD1CD274LMNAALDH1A1HTT | |
| SCHEMBL11202177 | 0.81 | POLB (0.37) | PDCD1CD274LMNAALDH1A1HTT | |
| SCHEMBL11435523 | 0.81 | IDO1 (0.42) | SMN1; SMN2RAB9AMAPK1TDP1POLB | |
| SCHEMBL11197019 | 0.80 | HTR7 (0.49) | PDCD1CD274LMNAALDH1A1HTT | |
| SCHEMBL11212389 | 0.78 | NPC1 (0.47) | ALDH1A1HTR7SMN1; SMN2RAB9AMAPK1 | |
| SCHEMBL9717406 | 0.77 | PDCD1 (0.47) | PDCD1CD274ALDH1A1HTR7SMN1; SMN2 | |
| SCHEMBL29699190 | 0.77 | PDCD1 (0.47) | PDCD1CD274ALDH1A1HTR7SMN1; SMN2 | |
| SCHEMBL11199823 | 0.77 | THRB (0.36) | PDCD1CD274LMNAALDH1A1HTT | |
| SCHEMBL17697636 | 0.76 | PDCD1 (0.55) | PDCD1CD274ALDH1A1HTR7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |