Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11283380 | 0.92 | ALDH1A1 (0.51) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11198998 | 0.82 | KMT2A (0.48) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9786163 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10550253 | 0.81 | ALDH1A1 (0.47) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9786144 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9837371 | 0.78 | LMNA (0.60) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9775880 | 0.78 | KMT2A (0.45) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL16469277 | 0.77 | KMT2A (0.50) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11008488 | 0.77 | LMNA (0.52) | KMT2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9382762 | 0.77 | KMT2A (0.73) | KMT2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4382937-A | Naphthyridine derivatives and their use as anti-bacterials | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |