Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10339014 | 0.83 | LDHA (0.54) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL3388456 | 0.81 | LDHA (0.57) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL4624766 | 0.81 | LDHA (0.57) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL3388461 | 0.81 | LDHA (0.57) | LDHAALOX15ALOX12CA2STAT3 | |
| Terameprocol SCHEMBL29794162 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2STAT3 | |
| Terameprocol SCHEMBL194588 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2STAT3 | |
| Terameprocol SCHEMBL30094578 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2STAT3 | |
| Terameprocol SCHEMBL10060164 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2STAT3 | |
| Terameprocol SCHEMBL2356280 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL806723 | 0.80 | CA2 (0.63) | LDHAALOX15ALOX12CA2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4415572-A | CARDIOTONIC AND INOTROPIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |