Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884878 | 0.85 | FOS (0.69) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL28760277 | 0.85 | FOS (0.44) | LDHAALOX15ALOX12FOSTTR | |
| SCHEMBL4254158 | 0.84 | LDHA (0.56) | LDHAALOX15ALOX12CA2FOS | |
| SCHEMBL7355462 | 0.83 | PDE4A (0.52) | — | |
| SCHEMBL11200364 | 0.83 | LDHA (0.58) | LDHAALOX15ALOX12CA2FOS | |
| SCHEMBL18526003 | 0.82 | ALOX15 (0.57) | LDHAALOX15ALOX12CA2FOS | |
| SCHEMBL9405351 | 0.81 | LDHA (0.53) | LDHAALOX15ALOX12CA2FOS | |
| Hydrochloric Acid SCHEMBL9352870 | 0.80 | LDHA (0.51) | LDHAALOX15ALOX12CA2ATM | |
| SCHEMBL12613921 | 0.80 | LDHA (0.51) | LDHAALOX15ALOX12CA2FOS | |
| Terameprocol SCHEMBL194588 | 0.80 | ALOX15 (0.77) | LDHAALOX15ALOX12CA2FOS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2138163-A | — | — | None | — | — | JP | disclosed |
| WO-2022140372-A1 | METHODS FOR PRODUCING D-α-METHYLDOPA | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20110124634-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PONIARD PHARMACEUTICALS, INC. | 2011-05-26 | — | — | US | disclosed |
| JP-H02138163-A | NONLINEAR OPTICAL MATERIAL COMPOSED OF CONJUGATED ORGANIC AMINE SALT | TEIJIN LTD | 1990-05-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124634-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | PARK7, BDNF, BACE1 | LDHA 3094/4885ALOX15 95/4885ALOX12 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.