Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203994 | 0.90 | ALDH1A1 (0.47) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11203292 | 0.82 | KMT2A (0.38) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11200451 | 0.81 | LMNA (0.38) | MAPTALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL11198016 | 0.80 | PRKCI (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL13780234 | 0.79 | ENPP2 (0.38) | MAPTKMT2AALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL11204595 | 0.79 | PRKCI (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL11203861 | 0.79 | P2RX3 (0.41) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11205242 | 0.78 | MAPT (0.45) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11200422 | 0.74 | KDM4E (0.41) | MAPTKMT2AALDH1A1MEN1HPGD | |
| SCHEMBL11197619 | 0.74 | KDM4E (0.35) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |