Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.57 |
| ▸ | MMP2 | P08253 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP3 | P08254 | 3/20 | 0.52 |
| ▸ | MMP7 | P09237 | 3/20 | 0.52 |
| ▸ | MMP9 | P14780 | 3/20 | 0.52 |
| ▸ | MMP13 | P45452 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055286 | 1.00 | FPR2 (0.57) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11062424 | 0.87 | FPR2 (0.47) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11202913 | 0.84 | DGAT1 (0.48) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL11202915 | 0.84 | DGAT1 (0.48) | MMP2MMP1MMP3MMP7MMP9 | |
| SCHEMBL11196969 | 0.83 | ALDH1A1 (0.47) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11056045 | 0.83 | ALDH1A1 (0.47) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL16007883 | 0.83 | FPR2 (0.77) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11055269 | 0.82 | KMT2A (0.49) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11196935 | 0.82 | KMT2A (0.49) | FPR2MMP2MMP1MMP3MMP7 | |
| SCHEMBL11194098 | 0.79 | MAPT (0.67) | MMP2MMP1MMP3MMP7MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411912-A | Insecticidal isovaleric acid esters | ZOECON CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
| US-4252724-A | Novel compositions | ZOECON CORPORATION (US) | 1981-02-24 | — | — | US | disclosed |
| US-4243819-A | Substituted amino acids | ZOECON CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4231953-A | Fluoro substituted aryl esters and thiolesters of amino acids | ZOECON CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4200758-A | 2,4-Imidazolidinedionylmethyl esters and thiolesters of anilino acids | ZOECON CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |