SCHEMBL16007883

SCHEMBL16007883

CC(C)[C@H](NC(=O)Nc1ccc(Br)cc1F)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.77
LMNA P02545 6/20 0.57
ALDH1A1 P00352 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.52
POLB P06746 1/20 0.51
MAPK1 P28482 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 2/20 0.49
HTT P42858 2/20 0.49
GAA P10253 1/20 0.49
HPGD P15428 1/20 0.49
ALOX12 P18054 1/20 0.49
CASP3 P42574 1/20 0.49
SENP7 Q9BQF6 1/20 0.49
SENP6 Q9GZR1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22506221 0.87 FPR2 (1.00) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL14937931 0.87 FPR2 (1.00) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL14948919 0.87 FPR2 (1.00) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL11200596 0.83 FPR2 (0.57) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL11055286 0.83 FPR2 (0.57) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL23129901 0.81 FPR2 (0.72) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL20484217 0.81 FPR2 (0.65) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL14903118 0.81 FPR2 (0.65) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL28348165 0.80 FPR2 (0.77) FPR2LMNAALDH1A1SMN1; SMN2NPC1
SCHEMBL16588643 0.80 FPR2 (0.77) FPR2LMNAALDH1A1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964213-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2016-01-13 EP claimed
EP-2964214-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2016-01-13 EP claimed
WO-2014138037-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-12 WO claimed
WO-2014138046-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-12 WO claimed
US-20140256684-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-11 US claimed
US-20140256685-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-11 US claimed
EP-3795148-B1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN INC (US) 2025-06-18 EP disclosed
EP-3795148-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2021-03-24 EP disclosed
EP-3795148-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2021-03-24 EP disclosed
US-10899780-B2 Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases ALLERGAN, INC. (US) 2021-01-26 US disclosed
US-20210008085-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN INC (US) 2021-01-14 US disclosed
US-20210008085-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN INC (US) 2021-01-14 US disclosed
US-20210000846-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN INC (US) 2021-01-07 US disclosed
US-20170216326-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. 2017-08-03 US disclosed
WO-2014138037-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-12 WO disclosed
WO-2014138046-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-12 WO disclosed
US-20140256684-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-11 US disclosed
US-20140256684-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES ALLERGAN, INC. (US) 2014-09-11 US disclosed
US-20140256685-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-11 US disclosed
US-20140256685-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES ALLERGAN, INC. (US) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210008085-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES FPR2, FPR1, FPR3 FPR2 1/4885LMNA 3347/4885ALDH1A1 4552/4885
US-20140256685-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES FPR2, FPR1, FPR3 FPR2 1/4885LMNA 3347/4885ALDH1A1 4552/4885
US-20170216326-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES FPR2, FPR1, FPR3 FPR2 1/4885LMNA 3347/4885ALDH1A1 4552/4885
US-20210000846-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING DERMATOLOGICAL DISEASES FPR2, FPR1, FPR3 FPR2 1/4885LMNA 3347/4885ALDH1A1 4552/4885
US-20140256684-A1 USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES FPR2, FPR1, FPR3 FPR2 1/4885LMNA 4475/4885ALDH1A1 4021/4885
US-10899780-B2 Use of agonists of formyl peptide receptor 2 for treating ocular inflammatory diseases FPR2, FPR1, FPR3 FPR2 1/4885LMNA 4475/4885ALDH1A1 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.