Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200278 | 0.85 | HRH4 (0.36) | HRH4ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL11199749 | 0.85 | HRH4 (0.36) | HRH4HPGDALDH1A1MAPTMAPK1 | |
| SCHEMBL11201110 | 0.85 | HRH4 (0.36) | HRH4ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL11204593 | 0.83 | ABCB1 (0.43) | HPGDALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL11203366 | 0.80 | KHK (0.41) | HRH4ALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL11198545 | 0.80 | HRH4 (0.42) | HRH4ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL11209421 | 0.78 | BCL2 (0.34) | HRH4ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL11201322 | 0.78 | MEN1 (0.43) | HPGDALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL11204627 | 0.78 | MAPT (0.42) | HPGDALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL11200734 | 0.78 | HTR3A (0.41) | HRH4ALDH1A1MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |