Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19690491 | 0.69 | SMN1; SMN2 (0.40) | SMN1; SMN2OPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL9416753 | 0.68 | ALDH1A1 (0.49) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL26862448 | 0.68 | ALDH1A1 (0.45) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL27535372 | 0.67 | GAA (0.40) | TSHRALDH1A1NPC1RAB9AGAA | |
| SCHEMBL9416778 | 0.66 | ALDH1A1 (0.46) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL30183273 | 0.66 | TSHR (0.40) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 | |
| Biphenyl SCHEMBL5571790 | 0.65 | TSHR (0.54) | TSHRSMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL28757628 | 0.65 | TSHR (0.41) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL25401575 | 0.64 | ITGB1 (0.48) | SMN1; SMN2OPRM1NPC1RAB9AKDM4E | |
| SCHEMBL6315068 | 0.64 | OPRM1 (0.40) | TSHRSMN1; SMN2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022087-B1 | STABILIZERS FOR THERMOPLASTS THAT CONTAIN CHLORINE | CIBA-GEIGY AG (CH) | 1983-11-23 | — | — | EP | claimed |