Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18663302 | 0.78 | ALOX5 (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL18663265 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL11200738 | 0.69 | TSHR (0.42) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9416753 | 0.68 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL18663303 | 0.68 | CACNA1D (0.39) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL9416778 | 0.66 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| Biphenyl SCHEMBL5571790 | 0.65 | TSHR (0.54) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL26862448 | 0.65 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| Biphenyl SCHEMBL927814 | 0.64 | MEN1 (0.67) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL6315068 | 0.64 | OPRM1 (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2019-06-06 | — | — | US | disclosed |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | RENQIU LIHE TECH LTD (CN) | 2017-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169328-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, GTF2I, POF1B | SMN1; SMN2 1503/4885ALDH1A1 2055/4885HPGD 2103/4885 |
| US-20170355792-A1 | OLEFIN POLYMERIZATION CATALYST CARRIER, SOLID CATALYST COMPONENT AND USE THEREOF | COG2, COG7, COG4 | SMN1; SMN2 3127/4885ALDH1A1 2496/4885HPGD 2434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.