Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25372952 | 1.00 | CYP2D6 (0.32) | CYP2D6CYP2C19 | |
| SCHEMBL16847599 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL19859578 | 0.78 | CTSC (0.39) | CYP2D6CYP2C19 | |
| SCHEMBL30171020 | 0.77 | — | — | |
| SCHEMBL9109510 | 0.77 | — | — | |
| SCHEMBL15969357 | 0.77 | — | — | |
| SCHEMBL13616171 | 0.73 | CA2 (0.36) | — | |
| SCHEMBL5741604 | 0.71 | — | — | |
| SCHEMBL24568584 | 0.70 | DPP4 (0.30) | — | |
| SCHEMBL25360604 | 0.69 | ALDH1A1 (0.39) | CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321123-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LasB | HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| EP-4204397-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASB | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-07-05 | — | — | EP | disclosed |
| EP-2280707-A1 | ALPHA2B AND ALPHA2C AGONISTS | Allergan, Inc. (US) | 2011-02-09 | — | — | EP | disclosed |
| WO-2009137340-A1 | ALPHA2B AND ALPHA2C AGONISTS | ALLERGAN, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321123-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LasB | SERPINB1, LTA, TFPI | CYP2D6 4233/4885CYP2C19 3769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.