Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199749 | 0.91 | HRH4 (0.36) | ALDH1A1NPSR1PRKCIMAPTKDM4E | |
| SCHEMBL11201922 | 0.89 | KDM4E (0.38) | ALDH1A1NPSR1PRKCIMAPTKDM4E | |
| SCHEMBL11203905 | 0.87 | PRKCI (0.35) | ALDH1A1NPSR1PRKCIMAPTKDM4E | |
| SCHEMBL11197420 | 0.83 | KDM4E (0.35) | ALDH1A1NPSR1MAPTKDM4EMAPK1 | |
| SCHEMBL11208073 | 0.81 | MAPT (0.33) | ALDH1A1NPSR1MAPTKDM4EMAPK1 | |
| SCHEMBL11209421 | 0.80 | BCL2 (0.34) | ALDH1A1MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL11201197 | 0.79 | LMNA (0.38) | ALDH1A1MAPTKDM4EMAPK1L3MBTL1 | |
| SCHEMBL11200451 | 0.79 | LMNA (0.38) | ALDH1A1NPSR1PLA2G1BATG4BMAPT | |
| SCHEMBL11204226 | 0.78 | ALDH1A1 (0.50) | ALDH1A1NPSR1PRKCIMAPTKDM4E | |
| SCHEMBL11207726 | 0.77 | HPGD (0.31) | ALDH1A1NPSR1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |