Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199749 | 0.88 | HRH4 (0.36) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11201110 | 0.88 | HRH4 (0.36) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11201827 | 0.85 | KDM4E (0.35) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11203991 | 0.82 | HTR2A (0.38) | BCL2MCL1HRH4KDM4EALDH1A1 | |
| SCHEMBL11201040 | 0.80 | ALDH1A1 (0.36) | KDM4EALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL11205773 | 0.79 | HRH4 (0.36) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11205447 | 0.78 | HRH4 (0.38) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11203905 | 0.78 | PRKCI (0.35) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11201922 | 0.76 | KDM4E (0.38) | HRH4HTR3AKDM4EALDH1A1MAPT | |
| SCHEMBL11200185 | 0.76 | ALDH1A1 (0.39) | HRH4HTR3AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |